Read Our Latest Monthly Round Up
Explore our latest featured articles, reports, highlights and more
Genome Biology
About   How to Submit  
Editorial Board   Article Alerts

Dear Colleague,



Genome Biology is pleased to share with you our January content update, featuring journal news, top articles and our most recent table of contents.

Journal news


Chief Editor Barbara Cheifet will be attending and speaking at the Lorne Genome Conference from February 17-19th.

Senior Editor Yixin Yao will be attending the Keystone Genome Engineering: From Mechanisms to Therapies conference in Victoria, British Columbia from February 19th-23rd. Email us to set up a meeting.

Genome Biology
and its sister journals BMC Biology and Genome Medicine now provide the opportunity for co-submissions, where authors submit a manuscript for joint consideration at two of these journals at the same time. Co-submissions provide a faster publication process, saving authors’ time and avoiding the need for multiple submissions. You can learn more about co-submissions here.

From 1st January 2019, all research reviewed at Genome Biology will undergo transparent peer review. Please see our Editorial for more details.

Featured articles

Oh et al

Implications of circadian oscillations of cytosine on epigenetic variability, aging, and complex disease

Oh and colleagues highlight that circadian oscillations in cytosine modification can have an impact on aging and common diseases in later life.

Hansen et al

Comparison of human gut bacteria in populations of rural Africa and the US

Hansen et al compare the gut microbiota of rural populations in Tanzania and Botswana and individuals living in the US city of Philadelphia.

Zhu et al

Re-designed guide RNAs boost CRISPR-pooled screens

Zhu and colleagues improve genetic screens by using innovative modified guide RNAs with internal barcodes integrated into their structure.

Table of contents



Keen on the tenure track, are you? Know these things, you should


Where is genomics going next?



Evolutionary genomics: the fruits of genomic approaches applied to evolutionary biology



iGUIDE: an improved pipeline for analyzing CRISPR cleavage specificity

Bushman et al. 


Degradation of endogenous proteins and generation of null-like phenotype in zebrafish using Trim-Away technology

Tang et al


Recombination of ecologically and evolutionarily significant loci maintains genetic cohesion in the Pseudomonas syringae species complex

Guttman et al


Circadian oscillations of cytosine modification in humans contribute to epigenetic variability, aging, and complex disease
Petronis et al

GC-biased gene conversion conceals the prediction of the nearly neutral theory in avian genomes
Mugal et al

Systematic evaluation of C. elegans lincRNAs with CRISPR knockout mutants

Shan et al. 


Exosomal miR-196a derived from cancer-associated fibroblasts confers cisplatin resistance in head and neck cancer through targeting CDKN1B and ING5

Zhang et al. 


Population structure of human gut bacteria in a diverse cohort from rural Tanzania and Botswana

Tishkoff et al


Multiple-gene targeting and mismatch tolerance can confound analysis of genome-wide pooled CRISPR screens

Martin et al


Genomic introgression through interspecific hybridization counteracts genetic bottleneck during soybean domestication

Wang, Chen and Ma


Correction to: RNA G-quadruplexes at upstream open reading frames cause DHX36- and DHX9-dependent translation of human mRNAs

Balasubramanian et al. 


Correction to: Applications and potential of genome editing in crop improvement

Goa et al





An amplicon-based sequencing framework for accurately measuring intrahost virus diversity using PrimalSeq and iVar

Andersen et al.  


Accurate prediction cell type-specific transcription factor binding

Keilwagen, Posch and Grau


Prediction of functional microRNA targets by integrative modeling of microRNA binding and target expression data

Liu and Wang


Guide RNAs with embedded barcodes boost CRISPR-pooled screens

Wei et al




The Network of Cancer Genes (NCG): a comprehensive catalogue of known and candidate cancer genes from cancer sequencing screens

Ciccarelli et al.




plyranges: a grammar of genomic data transformation

Lee, Cook and Lawrence

Submit your research

Genome Biology is fully open access, giving high visibility to your work.

  • Ranked 2nd among research journals in the Genetics and Heredity category of the JCR* – the highest open access journal within the category

  • Dedicated to excellent author service – the status of your manuscript will be constantly monitored with handling editors proactively communicating updates

  • Global visibility – published articles achieve high visibility through our engaging homepage and press releases of papers. We also have a Facebook page with over 32,000 followers and a highly active Twitter account, which has over 59,000 followers


  Submit your research today  
Follow us on:
Genome Biology on Twitter   Genome Biology on Facebook   BMC on YouTube   Linkedin
Transfer Desk
Imagine a world where you only have to submit your article once. With our Transfer Desk, we’re working toward making that a reality. Learn more

*2017 Journal Citation Reports® (Clarivate Analytics, 2018) 

This is how to ensure we´re always delivering our latest content to your inbox.

You have received this message as a result of opting in to hear from the journals or subject areas you've specified, BMC events, webinars and community news. To modify your subscription (including adding or removing subjects), click here.

Use this unsubscribe link to stop receiving any further messages from BMC.

For further information or enquiries please use our Contact page details.

BMC respects your privacy and does not disclose, sell or rent your personal information to any nonaffiliated third parties without your consent. Privacy Policy.

BioMed Central Ltd.
The Campus, 4 Crinan Street,
London, N1 9XW, 
United Kingdom
SpringerNature logo
©2019 BioMed Central | Part of Springer Nature