BMC Biology Table of Contents - February 2019
The circadian clock in three dimensions, stars in regeneration, and more
BMC Biology
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Dear Colleague,

From Golden Death bacteria to sea stars, this month’s content in BMC Biology comprises a diverse assortment of Research and Commissioned pieces.

Our research articles below include the identification of functional long non-coding RNAs in C. elegans and deciphering the role of actomyosin contractility in Notch signalling. Our front matter content includes the latest “Open Questions Biology” piece from our Editorial Board on mechanics of morphogenesis and a review on the structural aspects of circadian oscillator proteins.

The latest piece in our series In the Light of Evolution arrived this month detailing the transcriptome, proteome and draft genome of Euglena gracilis. Don’t forget you can still submit to our upcoming special issues on Cancer Metabolism, Engineering Biology and Microbiome Biology too!

Our Focus collection across the BMC flagship journals is on Cancer. Don’t miss reviews on immunotherapy, combatting resistance, the evolution and cancer – the evolutionary history of single tumors and a look at how evolutionary thinking is essential to understand and tackle cancer.

Meet the Editor: Our Chief Editor Mirna Kvajo will be attending the meeting Mitotic spindle: From living and synthetic systems to theory on 24-27 March in Split, Croatia; while our Deputy Editor Graham Bell will be attending the Keystone Symposia 3D Genome: Gene Regulation and Disease on 17-21 March in Banff, Canada. Learn about our Editorial team here.

If you have any questions, or if you would like to inquire about the potential suitability of a manuscript for publication in BMC Biology don't hesitate to contact us at

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Featured articles
The circadian clock in three dimensions
The circadian clock in three dimensions

Our latest Review discusses the 3D structures of circadian clock components; and how these inform us on biological time keeping. Read the rest of our Reviews collection here!

Examining hard-to-penetrate surfaces
Accelerating crop production

The newest addition to our Environment and Sustainability series - Lee Hickey and colleagues cover the pressures facing agriculture, and how plant breeding may be sped-up.

A sea star in regeneration
A (Sea) Star in Regeneration

Metazoan lineages exhibit a wide range of regenerative capabilities, which vary across developmental stages and tissues. Now Cary et al detail the whole-body regenerative ability of sea stars, and reveal the deep similarity of these processes across the metazoa.

Exploring function in the non-coding genome
Exploring function in the non-coding genome

Akay and colleagues present an expanded set of annotated long non-coding RNAs in C. elegans, and through functional validation of selected candidates, suggest that a significant proportion of these may have biological function.

From the blog - a Golden Death for parasitic worms
Golden Death for parasitic worms

In this blog post, Tony Page discusses his group’s paper, also published in BMC Biology this month, on how a recently discovered bacterium can digest worms from the inside out, and may be useful as a future biocontrol agent.

Featured series - New Tools for Neurobiology
New Tools for Neurobiology

This series, comprising Reviews, Q&As, and original research, covers new and emerging techniques and technologies that are transforming neuroscience; includes commissioned pieces on Expansion Microscopy, Optogenetics and Tissue Clearing, and Electron Microscopy. 

Table of contents

Commissioned content


Q&A: modern crop breeding for future food security

Kai P. Voss-Fels, Andreas Stahl and Lee T. Hickey


Open questions: how to get developmental biology into shape?
Timothy E. Saunders and Philip W. Ingham


Role of self-organising myddosome oligomers in inflammatory signalling by Toll-like receptors 
Nicholas J. Gay


Circadian oscillator proteins across the kingdoms of life: structural aspects 
Reena Saini, Mariusz Jaskolski and Seth J. Davis




The golden death bacillus Chryseobacterium nematophagum is a novel matrix digesting pathogen of nematodes

Antony P. Page, Mark Roberts, Marie-Anne Félix, Derek Pickard, Andrew Page and William Weir

Analysis of sea star larval regeneration reveals conserved processes of whole-body regeneration across the metazoa 
Gregory A. Cary, Andrew Wolff, Olga Zueva, Joseph Pattinato and Veronica F. Hinman

Identification of functional long non-coding RNAs in C. elegans 
Alper Akay, David Jordan, Isabela Cunha Navarro, Tomasz Wrzesinski, Chris P. Ponting, Eric A. Miska and Wilfried Haerty


A role for actomyosin contractility in Notch signaling 
Ginger L. Hunter, Li He, Norbert Perrimon, Guillaume Charras, Edward Giniger and Buzz Baum


Transcriptome, proteome and draft genome of Euglena gracilis
ThankGod E. Ebenezer, Martin Zoltner, Alana Burrell et al

Reasons to publish with us

Hospitable publishing process
. BMC Biology offers rapid evaluation and clear and continuous communication on the progress of your manuscript.


High visibility. All content is open access immediately on publication. Papers that are published in BMC Biology are featured on our website with article-level metrics and promoted via press releases, blogs and social media.

Flexible formatting. To facilitate the submission process, we are flexible with regard to the format, style and length of initial submissions.

Scoop protection. BMC Biology offers "scoop protection", meaning that if other researchers publish similar findings after submission, or post them on a preprint server, this will not be a reason for rejection.

Portable peer review. We support authors who wish to transfer a paper reviewed at BMC Biology to a journal of their choice. We are also able to consider manuscripts on the basis of reviews rejected at other journals, including those outside of BMC and Springer Nature. Find out more at our peer review policy page.

Co-submissions to other BMC ‘flagship’ journals. If a paper is potentially appropriate in scope for BMC Biology and Genome Biology or Genome Medicine authors have the opportunity to submit a manuscript for joint consideration at two of these journals at the same time. Learn more here.


Innovative practices and policies. Our re-review opt out policy allows authors to choose whether reviewers see their revisions, minimizing the time to publication. The innovative Registered Reports article format supports transparency and minimizes research and publication bias.

bioRxiv transfers. BMC Biology is happy to consider manuscripts that have been, or will be, posted on a preprint server. Authors are able to submit their manuscripts directly from bioRxiv, without having to re-upload files.

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Best regards,

The BMC Biology Editorial Team

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