BMC Biology Table of Contents - April 2019
 
Cell size sensing, cargo transfer during sperm maturation, olfactory ionotropic receptors, and more
 
 
 
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Dear Colleague,
 
 
 

This month’s content in BMC Biology includes our usual diverse assortment of Research and frontmatter content, as well as the first pieces from our upcoming special interest collections.  

Our Microbiome Biology special issue – a collaboration with our sister journal Genome Biology – launches in May. The lead piece, showing the abundance of antibiotic resistance genes in bird microbiomes across the world, can be found below, accompanied by an author blog. The first piece from our Cancer Metabolism collection also arrives this month, detailing predictive models for cell-line specific dependence on metabolic genes. Keep an eye out for these collections in the near future! We also added research presenting a canine GI organoid system for translational studies of intestinal diseases to the Engineering Biology series. Don’t forget you can still submit your research to all of our ongoing series from our homepage!


Each month the BMC flagships showcase a Focus collection – this month on pathogens. Don’t miss a Q&A on pathogens and how they have shaped human history, a Review on how genomic approaches have been used to understand dengue and two pieces on Zika, a Review on Zika vaccines and their future challenges, and a commentary on the development of Zika vaccines.


BMC Biology supports portable peer review by sharing reviews and evaluating papers based on existing reports. Interested in submitting? Learn more from our new Transfers and Portable Peer Review Policy and Editorial.

Our archived eTOCs are available on our Goings On page, along with news and announcements from BMC Biology.

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Featured articles
 
 
 
Dynamin mediated cargo transfer
Dynamin-mediated cargo transfer during sperm maturation

Research from Brett Nixon and colleagues finds that a spatial relocation of dynamin within the maturing sperm head promotes the transfer of proteins from extracellular epididymal vesicles.

 
 
 
Cell size sensing
Cell size sensing

In this Opinion Article, Ida Rishal and Mike Fainzilber propose a one-dimensional cytoskeletal length-sensing mechanism to solve the three-dimensional problem of regulating cell size.

 
 
 
Olfactory ionotropic receptors
Olfactory ionotropic receptors

Liliane Albuin, Richard Benton and colleagues illuminate the biology of this family of receptors, providing insights into their in vivo assembly into heteromeric complexes, and trafficking to the surface of ciliated sensory neurons in Drosophila.

 
 
 
Enabling behavioural epigenetics in drosophila
Enabling behavioural epigenetics in Drosophila

Clement Kent and colleagues describe how to obtain an improved yield of cell-type specific nuclei for ChIP-seq analysis, and report on the epigenetic consequences of social isolation in Drosophila dopaminergic neurons.

 
 
 
 
From the blog: the canary in the superbug mine
 
 
 
Canary in the superbug mine

Wille, Marcelino, Sorrell and Holmes discuss their recent paper, published in BMC Biology this month, on how metatranscriptomics shows that antibiotic resistance genes can be found in bird microbiomes across the world, including as remote as penguins in Antarctica, and how human sewage might be contributing to this.

 
 
 
Featured series - Environment and Sustainability
 
 
 
Featured series - Environment and Sustainability

This collection brings together Research articles and frontmatter content that address questions in ecology, sustainability and the environmental challenges of the Anthropocene: from Research on modelling the impact of genetic controls on malaria populations and genome analysis of rice subspecies to understand their agronomic traits, to a Q&A on how modern crop breeding can be used for future food security.

 
 
 
Table of contents
 
 
 

Commissioned content

OPINION
Cell size sensing - a one-dimensional solution for a three-dimensional problem?
Ida Rishal and Mike Fainzilber

 
 
 
 

Research

RESEARCH ARTICLE

Inferring cancer dependencies on metabolic genes from large-scale genetic screens

Shoval Lagziel, Won Dong Lee and Tomer Shlomi

RESEARCH ARTICLE
Mechanisms of tethering and cargo transfer during epididymosome-sperm interactions
Wei Zhou, Simone J. Stanger, Amanda L. Anderson, Ilana R. Bernstein, Geoffry N. De Iuliis, Adam McCluskey, Eileen A. McLaughlin, Matthew D. Dun and Brett Nixon

RESEARCH ARTICLE
In vivo assembly and trafficking of olfactory lonotropic Receptors
Liliane Abuin, Lucia L. Prieto-Godino, Haiyun Pan, Craig Gutierrez, Lan Huang, Rongsheng Jin and Richard Benton

RESEARCH ARTICLE
Derivation of adult canine intestinal organoids for translational research in gastroenterology
Lawrence Chandra et al

RESEARCH ARTICLE

Enabling cell-type-specific behavioral epigenetics in Drosophila: a modified high-yield INTACT method reveals the impact of social environment on the epigenetic landscape in dopaminergic neurons
Pavan Agrawal, Phuong Chung, Ulrike Heberlein and Clement Kent

RESEARCH ARTICLE
Meta-transcriptomics reveals a diverse antibiotic resistance gene pool in avian microbes
Vanessa R. Marcelino, Michelle Wille, Aeron C. Hurt, Daniel González-Acuña, Marcel Klaassen, Timothy E. Schlub, John-Sebastian Eden, Mang Shi, Jonathan R. Iredell, Tania C. Sorrell and Edward C. Holmes

 
 
 
 
 
 
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