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Dear Colleague,

 

 

Genome Biology is pleased to share with you our May content update, featuring journal news, top articles and our most recent table of contents.

 
 
Journal news

 
 

The special issue on Microbiome Biology, guest edited by Rob Knight (UC San Diego, USA), Ruth Ley (MPI for Developmental Biology, Tuebingen, Germany), Elizabeth Grice (University of Pennsylvania, USA) and Jeroen Raes (KU Leuven, Belgium), has launched. The special issue, joint with BMC Biology, will be publishing research, methods, and reviews covering diverse areas of microbiome research. Look for our content being published over the next several months here.

 
 
Featured articles

 
 
 
Fiorucci et al

Mechanisms of a COMPASS-like complex in Arabidopsis

Fiorucci et al. show that the COMPASS-like complex mediates H3K4me3 deposition in Arabidopsis using an H2B monoubiquitin-independent pathway

 
 
 
13q12.12 locus

Biological significance of the 13q12.12 locus in lung cancer risk

A study looks into the mechanism for how lung cancer risk is associated with the 13q12.12 locus, showing involvement of a novel p53-responsive enhancer.

 
 
 
CellTag Indexing

CellTag Indexing: genetic barcode-based sample multiplexing for single-cell genomics


A new single-cell method that uses predefined genetic barcodes and enables pooled samples to be tagged and tracked over time in vitro and in vivo.

 
 
 
 
Table of contents
 
 
 


Comment

EDITORIAL

Next-generation genome annotation: we still struggle to get it right
Steven L. Salzberg

MEETING REPORT
At the forefront of the sequencing revolution - notes from the RNGS19 conference

Sander Wuyts and Nicola Segata

RESEARCH HIGHLIGHT
One reference genome is not enough

Xiaofei Yang et al.

RESEARCH HIGHLIGHT
Mouse microbiomes: overlooked culprits of experimental variability

Maria-Luisa Alegre

RESEARCH HIGHLIGHT
Genome-wide analysis of DNA replication timing in single cells: Yes! We're all individuals

Anne D. Donaldson and Conrad A. Nieduszynski

 
 
 

Review

OPINION
Genomics and data science: an application within an umbrella

Fábio C. P. Navarro et al.

Research

SHORT REPORT
Addressing confounding artifacts in reconstruction of gene co-expression networks

Princy Parsana et al.

SHORT REPORT
Isolation of novel gut bifidobacteria using a combination of metagenomic and cultivation approaches

Gabriele Andrea Lugli et al.

SHORT REPORT
Human cleaving embryos enable robust homozygotic nucleotide substitutions by base editors

Meiling Zhang et al

RESEARCH
VULCAN integrates ChIP-seq with patient-derived co-expression networks to identify GRHL2 as a key co-regulator of ERa at enhancers in breast cancer

Andrew N. Holding et al.

RESEARCH
Genomic signatures accompanying the dietary shift to phytophagy in polyphagan beetles

Mathieu Seppey et al.

RESEARCH
Systematic analysis of dark and camouflaged genes reveals disease-relevant genes hiding in plain sight

Mark T. W. Ebbert et al

RESEARCH
Detection of circular RNA expression and related quantitative trait loci in the human dorsolateral prefrontal cortex

Zelin Liu et al

RESEARCH
Arabidopsis S2Lb links AtCOMPASS-like and SDG2 activity in H3K4me3 independently from histone H2B monoubiquitination

Anne-Sophie Fiorucci et al.

RESEARCH
The inherited variations of a p53-responsive enhancer in 13q12.12 confer lung cancer risk by attenuating TNFRSF19 expression

Lipei Shao et al.

METHOD
SCRABBLE: single-cell RNA-seq imputation constrained by bulk RNA-seq data

Tao Peng et al.

METHOD
CellTag Indexing: genetic barcode-based sample multiplexing for single-cell genomics

Chuner Guo et al.

METHOD
ChiCMaxima: a robust and simple pipeline for detection and visualization of chromatin looping in Capture Hi-C

Yousra Ben Zouari et al

METHOD
WhoGEM: an admixture-based prediction machine accurately predicts quantitative functional traits in plants
Laurent Gentzbittel et al

METHOD
OSCA: a tool for omic-data-based complex traits analysis

Futao Zhang et al.

 
 
 

Interactions

CORRECTION
Correction to: Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome

Warren A Cheung et al.

CORRESPONDENCE
Comments on the model parameters in "SiFit: inferring tumor trees from single-cell sequencing data under finite-sites models"

Hamim Zafar et al.

 
 
 
 
 
 
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