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Genome Biology is pleased to share with you our May content update, featuring journal news, top articles and our most recent table of contents.

Journal news


The special issue on Microbiome Biology, guest edited by Rob Knight (UC San Diego, USA), Ruth Ley (MPI for Developmental Biology, Tuebingen, Germany), Elizabeth Grice (University of Pennsylvania, USA) and Jeroen Raes (KU Leuven, Belgium), has launched. The special issue, joint with BMC Biology, will be publishing research, methods, and reviews covering diverse areas of microbiome research. Look for our content being published over the next several months here.

Featured articles

Fiorucci et al

Mechanisms of a COMPASS-like complex in Arabidopsis

Fiorucci et al. show that the COMPASS-like complex mediates H3K4me3 deposition in Arabidopsis using an H2B monoubiquitin-independent pathway

13q12.12 locus

Biological significance of the 13q12.12 locus in lung cancer risk

A study looks into the mechanism for how lung cancer risk is associated with the 13q12.12 locus, showing involvement of a novel p53-responsive enhancer.

CellTag Indexing

CellTag Indexing: genetic barcode-based sample multiplexing for single-cell genomics

A new single-cell method that uses predefined genetic barcodes and enables pooled samples to be tagged and tracked over time in vitro and in vivo.

Table of contents



Next-generation genome annotation: we still struggle to get it right
Steven L. Salzberg

At the forefront of the sequencing revolution - notes from the RNGS19 conference

Sander Wuyts and Nicola Segata

One reference genome is not enough

Xiaofei Yang et al.

Mouse microbiomes: overlooked culprits of experimental variability

Maria-Luisa Alegre

Genome-wide analysis of DNA replication timing in single cells: Yes! We're all individuals

Anne D. Donaldson and Conrad A. Nieduszynski



Genomics and data science: an application within an umbrella

Fábio C. P. Navarro et al.


Addressing confounding artifacts in reconstruction of gene co-expression networks

Princy Parsana et al.

Isolation of novel gut bifidobacteria using a combination of metagenomic and cultivation approaches

Gabriele Andrea Lugli et al.

Human cleaving embryos enable robust homozygotic nucleotide substitutions by base editors

Meiling Zhang et al

VULCAN integrates ChIP-seq with patient-derived co-expression networks to identify GRHL2 as a key co-regulator of ERa at enhancers in breast cancer

Andrew N. Holding et al.

Genomic signatures accompanying the dietary shift to phytophagy in polyphagan beetles

Mathieu Seppey et al.

Systematic analysis of dark and camouflaged genes reveals disease-relevant genes hiding in plain sight

Mark T. W. Ebbert et al

Detection of circular RNA expression and related quantitative trait loci in the human dorsolateral prefrontal cortex

Zelin Liu et al

Arabidopsis S2Lb links AtCOMPASS-like and SDG2 activity in H3K4me3 independently from histone H2B monoubiquitination

Anne-Sophie Fiorucci et al.

The inherited variations of a p53-responsive enhancer in 13q12.12 confer lung cancer risk by attenuating TNFRSF19 expression

Lipei Shao et al.

SCRABBLE: single-cell RNA-seq imputation constrained by bulk RNA-seq data

Tao Peng et al.

CellTag Indexing: genetic barcode-based sample multiplexing for single-cell genomics

Chuner Guo et al.

ChiCMaxima: a robust and simple pipeline for detection and visualization of chromatin looping in Capture Hi-C

Yousra Ben Zouari et al

WhoGEM: an admixture-based prediction machine accurately predicts quantitative functional traits in plants
Laurent Gentzbittel et al

OSCA: a tool for omic-data-based complex traits analysis

Futao Zhang et al.



Correction to: Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome

Warren A Cheung et al.

Comments on the model parameters in "SiFit: inferring tumor trees from single-cell sequencing data under finite-sites models"

Hamim Zafar et al.

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*2017 Journal Citation Reports® (Clarivate Analytics, 2018) 

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