BMC Biology Table of Contents - June 2019
 
Toolkit of ribosome biogenesis inhibitors, imprinted gene expression in the human genome, and more
 
 
 
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Dear Colleague,
 
 
 

This month’s content in BMC Biology includes our usual diverse assortment of Research and frontmatter content, and a look towards our upcoming special interest collections.

Research below covers a toolkit of ribosome biogenesis inhibitors, a high-resolution map of imprinted gene expression in the human genome, and the emergence of two cell fates from self-repressor circuits.

Two new articles are added to our Microbiome Biology special issue, a collaboration with our sister journal Genome Biology, on the extent of microbial "dark matter" and Research on how skin care products affect the chemistry and microbiome of the skin.

Our other collections - including Engineering Biology, Protein Quality Control, and In the Light of Evolution - can be accessed from our homepage and welcome submissions. July will mark the launch of our latest collection, on Cancer Metabolism: keep an eye out for further news and additions to the landing page!


Each month the BMC flagships showcase a Focus collection - this month on the immune system in health and disease. Featured are Research articles on the immune system and the hygiene hypothesisTreg cell differentiation trajectories and roles in immune tolerance, and immune cell regulation via methylation


BMC Biology supports portable peer review by sharing reviews and evaluating papers based on existing reports. Interested in submitting? Learn more from our new Transfers and Portable Peer Review Policy and Editorial.

Our archived eTOCs are available on our Goings On page, along with news and announcements from BMC Biology.

If you have any questions, or if you would like to inquire about the potential suitability of a manuscript for publication in BMC Biology, don’t hesitate to contact us at BMCBiologyEditorial@biomedcentral.com.


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Featured articles
 
 
 
Verger et al
Frontiers of the unknown in microbiome research

How far have we come, and how far to go? Nicola Segata and Andrew Maltez comment on the challenges of detection, characterization, and functional understanding present in any microbiome experiment.
 
 
 
Bouslimani et al
The impact of skin care products on skin microbiota and chemistry

A longitudinal study by Amina Bouslimani, Rob Knight, Pieter Dorrestein and colleagues report individualized changes in skin chemistry and composition of the microbiome in response to underarm deodorants and foot powder.
 
 
 
Kielbasa et al
Detecting parent-of-origin bias in gene expression

Szymon Kielbasa and colleagues find multiple imprinted genes through the analysis of family trios, including incomplete parental bias and differential expression of overlapping sense/antisense transcripts.
 
 
 
Awad et al

Drugging ribosome biogenesis

The multifaceted process of ribosome maturation represents a promising target for new disease therapeutics. Here, Awad et al present a comprehensive set of inhibitors to study ribosome biogenesis, by chemical inhibition of individual maturation steps.

 
 
 
 
Featured series - Reviews
 
 
 
Featured series - Reviews

This collection houses our commissioned Reviews, including the structural aspects of circadian clock components, “frozen metabolic accidents” in evolution, the axes of mammalian unfolded protein response, and the evolution of aging.

 
 
 
 
Table of contents
 
 
 

Commissioned content

COMMENT

Multiple levels of the unknown in microbiome research

Andrew Maltez Thomas and Nicola Segata

 
 
 
 

Research

RESEARCH ARTICLE

RNA-Seq in 296 phased trios provides a high-resolution map of genomic imprinting

Jadhav et al

RESEARCH ARTICLE
The emergence of the two cell fates and their associated switching for a negative auto-regulating gene

Jiang et al.  

RESEARCH ARTICLE
The impact of skin care products on skin chemistry and microbiome dynamics
Boislimani et al

RESEARCH ARTICLE
Inhibiting eukaryotic ribosome biogenesis

Awad et al. 

 
 
 
 
 
 
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