BMC Biology Table of Contents – January 2020
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Dear Colleague,

The first collection of BMC Biology papers from 2020 arrives below in our January table of contents.

Three papers present genome assemblies to provide insights into diverse aspects of animal biology: conservation genetics and heterozygosity (lion; Panthera leo); genomic substrates for success of invasive species (round goby; Neogobius melanostomus); and evolutionary approaches to improve genomes of disease vectors (Anopheles species).


You’ll also find Methodology articles on straightforward labelling of proteins and organelles for live-cell imaging, and in situ single-cell sequencing of the RNA editing landscape; along with research on restoring amyloid-mediated interneuron dysfunction, and the import pathway of mitochondrial carriers.


BMC Biology considers articles across the spectrum of biology, with particular interest in the topics of our on-going thematic series. Our collections on engineering in biology, protein quality control, techniques in neurobiology, environment and sustainability, and how evolutionary principles shed light on the biology around us, are all welcoming submissions. Follow the links to find out how to submit, and to read the collections!

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Our archived eTOC’s are available on our Goings On page, along with news and announcements from BMC Biology.

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Flagship Focus

Each month the BMC flagships showcase a Focus collection – this month on Disease Genetics. Follow these links for the featured articles from Genome BiologyGenome MedicineBMC Biology and BMC Medicine.

Featured articles

Nitrogen availability often limits crop yield Improving Anopheles genome assemblies
Improving Anopheles genome assemblies

Robert Waterhouse, Igor Sharakhov and colleagues present upgraded genome assemblies of 21 Anopheles species using an evolutionarily guided, three-method scaffolding workflow.

Full text | Download PDF
A map of RNA editing in the developing brain
A map of RNA editing in the developing brain

Elin Lundin and colleagues use in situ sequencing to reveal the spatiotemporal patterns of RNA editing during mouse brain development, identifying regional, and cell-type specific regulation.

Full text | Download PDF

Fine-tuning striatal glutamate release
Fine-tuning striatal glutamate release

Francisco Ciruela, Leonardo Pardo, Vicent Casadó, Sergi Ferré and colleagues show that cannabinoid-induced inhibition of glutamate release in the striatum is mediated via heterotetramer complexes of adenosine and cannabinoid receptors.

Full text
 | Download PDF

Two-pore channels in mTORC1 signalling
Two-pore channels in mTORC1 signalling

Catherine Pears and colleagues demonstrate a role for the two-pore channel protein and intracellular Ca2+ signalling in the regulation of mTORC1 activity upon starvation.

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Table of contents

Research Articles

Evolutionary superscaffolding and chromosome anchoring to improve Anopheles genome assemblies
Robert M. Waterhouse et al.
BMC Biology 2020 18:1

The mitochondrial carrier pathway transports non-canonical substrates with an odd number of transmembrane segments

Heike Rampelt et al.

BMC Biology 2020 18:2

Long live the king: chromosome-level assembly of the lion (Panthera leo) using linked-read, Hi-C, and long-read data

Ellie E. Armstrong et al.

BMC Biology 2020 18:3

A straightforward approach for bioorthogonal labeling of proteins and organelles in live mammalian cells, using a short peptide tag

Inbar Segal et al.

BMC Biology 2020 18:5

Spatiotemporal mapping of RNA editing in the developing mouse brain using in situ sequencing reveals regional and cell-type-specific regulation
Elin Lundin et al.

BMC Biology 2020 18:6


Optogenetic activation of parvalbumin and somatostatin interneurons selectively restores theta-nested gamma oscillations and oscillation-induced spike timing-dependent long-term potentiation impaired by amyloid β oligomers

Kyerl Park et al.

BMC Biology 2020 18:7


A two-pore channel protein required for regulating mTORC1 activity on starvation
Fu-Sheng Chang et al.
BMC Biology 2020 18:8

Control of glutamate release by complexes of adenosine and cannabinoid receptors
Attila Köfalvi et al.
BMC Biology
 2020 18:9

The mitochondrial HSP90 paralog TRAP1 forms an OXPHOS-regulated tetramer and is involved in mitochondrial metabolic homeostasis
Abhinav Joshi et al.
BMC Biology 2020 18:10

The round goby genome provides insights into mechanisms that may facilitate biological invasions
Irene Adrian-Kalchhauser et al.
BMC Biology 2020 18:11

Correction to: Common ancestry of heterodimerizing TALE homeobox transcription factors across Metazoa and Archaeplastida
Sunjoo Joo et al.
BMC Biology 2020 18:4

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The BMC Biology Editorial Team

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