BMC Biology Table of Contents – May 2020
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Dear Colleague,

BMC Biology is pleased to share with you our May content update, featuring journal news, selected article highlights, current open series, and our most recent table of contents.

Research papers this month cover considerations in releasing CRISPR-based genetically engineered mosquitoes, including the ability to confine and remediate released populations; and a simple web tool for comparing data from multiple biological networks and systems. Other papers include the mapping of susceptibility loci in psoriasis; a method for culturing marine species, including the extensive Spiralia; and a comprehensive picture on the origin of mitochondrial semiquinones – which do not originate from respiratory complex I.

Also present this month are articles on the evolutionary divergence of the yeast pathogen Candida albicans from a single hybrid ancestor; how the genomes of polar dinoflagellates may help understand how selection acts in complex genome structures to facilitate local adaptation; and the uncoupled evolutionary trajectories of mitochondrial and nuclear genomes. 


BMC Biology has a number of thematic series that are open and welcoming submissions of research articles, including Research Synthesis and Meta-research in Biology,  In the Light of Evolution, Cancer Metabolism, New Tools for Neurobiology, and Engineering Biology. See the full list here – and visit each series’ page for details of how to submit.

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Flagship focus

Each month the BMC flagships showcase a Focus collection – this month on Neurobiology in health and disease. Follow these links for the featured articles from Genome BiologyGenome MedicineBMC Biology and BMC Medicine.

Featured articles

Featured series – Reviews
Featured series – Reviews

This collection houses our commissioned Reviews, including the evolution of animal domestication, X-ray computed tomography in life sciences, protein assembly systems in natural and synthetic biology, and the microbiome of the upper respiratory tract in health and disease.
Genomic history of the Italian population
Genomic history of the Italian population

Marco Sazzini, Paolo Garagnani and colleagues retraced Italians' genetic history, showing early divergence and distinct adaptive evolution for people living in the north and south of Italy.

Full text | Download PDF

Whole-genome duplications and the evolution of hexapods
Whole-genome duplications and the evolution of hexapods

A comprehensive analysis of hexapod genomes by Dick Roelofs and colleagues finds limited evidence that WGD plays a significant role in the evolution of hexapods.

Full text | Download PDF

Network deficits in Huntington’s disease neuronal models
Network deficits in Huntington’s disease neuronal models

Jordi Alberch and colleagues examined the neuronal ensemble activity and network topology of Huntington’s disease model cultures, finding distinct network alterations in striatal and cortical neurons.

Full text | Download PDF

A novel genetic strategy to enhance in vitro hematopoiesis
A novel genetic strategy to enhance in vitro hematopoiesis

Christopher Thom, Ben Voight and colleagues define a role for TPM1 in constraining in vitro hematopoiesis and discuss the benefits of a computational approach for specification of trait-specific causal genetic variants for clinically relevant human traits.

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Table of contents

Research Articles

Methodology article
An automated aquatic rack system for rearing marine invertebrates
Jonathan Q. Henry et al.
BMC Biology 2020 18:46

Research article
Mapping DNA interaction landscapes in psoriasis susceptibility loci highlights KLF4 as a target gene in 9q31
Helen Ray-Jones et al.
BMC Biology 2020 18:47

Research article
Genomic evidence for a hybrid origin of the yeast opportunistic pathogen Candida albicans
Verónica Mixão and Toni Gabaldón
BMC Biology 2020 18:48

Research article
Discordant evolution of mitochondrial and nuclear yeast genomes at population level
Matteo De Chiara et al.
BMC Biology 2020 18:49

Research article
Modeling confinement and reversibility of threshold-dependent gene drive systems in spatially-explicit Aedes aegypti populations
Héctor M. Sánchez C. et al.
BMC Biology 2020 18:50

Research article
Tropomyosin 1 genetically constrains in vitro hematopoiesis
Christopher Stephen Thom et al.
BMC Biology 2020 18:52

Software article
NetConfer: a web application for comparative analysis of multiple biological networks
Sunil Nagpal et al.
BMC Biology 2020 18:53

Research article
Using a chimeric respiratory chain and EPR spectroscopy to determine the origin of semiquinone species previously assigned to mitochondrial complex I
John J. Wright et al.
BMC Biology 2020 18:54

Research article
Genomic history of the Italian population recapitulates key evolutionary dynamics of both Continental and Southern Europeans
Marco Sazzini et al.
BMC Biology 2020 18:51

Research article
Genomes of the dinoflagellate Polarella glacialis encode tandemly repeated single-exon genes with adaptive functions
Timothy G. Stephens et al.
BMC Biology 2020 18:56

Research article
Multi-faceted analysis provides little evidence for recurrent whole-genome duplications during hexapod evolution
Dick Roelofs et al.
BMC Biology 2020 18:57

Research article
Deficits in coordinated neuronal activity and network topology are striatal hallmarks in Huntington’s disease
S. Fernández-García et al.
BMC Biology 2020 18:58


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The BMC Biology Editorial Team

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